Systemic autoimmune diseases are characterized by the production of antibodies against a broad range of self-antigens. Recent evidence indicates that the majority of these autoantigens are modified in various ways during cell death. This has led to the hypothesis that the primary immune response in the development of autoimmunity is directed to components of the dying cell. In this article, we summarize data on the modification of autoantigens during cell death and the possible consequences of this for autoimmunity. BioEssays 22:627–636, (...) 2000. © 2000 John Wiley & Sons, Inc. (shrink)

Festschrift volume in honour of Mohd. Sabir Hussain, b. 1935.

Experimental results on spectra and wave functions of a ray-splitting microwave billiard are presented. The billiard is formed by a flat rectangular microwave cavity with a quarter-circle insert made of teflon in one of the corners. Using the Gutzwiller trace formula, the contribution of the periodic orbits of the billiard to the density of states are determined. The wave functions, many of them showing scars associated with periodic orbits, are interpreted in terms of the semiclassical Green function.

Relevance of research. Any religion in the world emphasizes the woman's femininity, namely an anthropological feature that does not require similarity with the functional features of her husband. However, in turn, it has the potential of a comprehensive development of the individual as a mother, and the realization of the role of women in society. The misconceptions that maternity lifts women's potential and suppresses their personal development causes a lot of controversial issues that lead to negative manifestations of gender inequality. (...) Negative manifestations of the perception of false positions lead to terrible structural changes in society, ruin the foundations of the laws of motherhood, have consequences of the aging of the nation, the loss of human spiritual humanism. Women lose the opportunity to feel like a mother and transfer their love of work to work as a child. Therefore, its main base anthropological identity is reduced to zero in this case and makes a woman "uncertain" gender, which will never find its place in society. The aim of the study.It based on the study of the anthropological horizons of gender inequality within the framework of religious canons and modern trends in the manifestation of business, the loss of anthropological value of women. The author's team has proved that each of the religions of the world pays much attention to women as mothers, their roles in society with exceptional abilities and special qualities. None of the religions does restrict women in revealing these abilities, but places anthropological peculiarity on the first place of a woman-mother, guardian of the family. Religion acts as a universal anthropological phenomenon, which reveals each individual essential element characteristic of every person and emphasizes its importance for society. (shrink)

From the beginning of the seventeenth century it has generally been held that the second Medicean is the parent of all the other extant manuscripts. In two articles C. W. Mendell has demonstrated that Leidensis B.P.L. 16. B is the manuscript once owned by Rudolphus Agricola and later by Th. Ryck, whose edition makes frequent allusion to its readings. Mendell's attempt to show further that L represents a tradition independent of the Medicean has found little support until recently, when E. (...) Koestermann, in the course of preparing the latest Teubner edition of Annals and Histories became convinced from his own study of L that Mendell's view—in spite of some arguments of dubious validity—was essentially correct. In an article in Philologus and in the preface to his edition of Histories Koestermann has marshalled the arguments which he believes prove L's independence of the Medicean line of descent. Since the new valuation that Koestermann puts upon L has produced a drastic revision of both text and apparatus criticus in his new editions, it may be worth while to examine the evidence that Koestermann adduces in support of his belief in L's independence. (shrink)

In 1826 Americans witnessed the spectacle of President John Quincy Adams and Vice-President John C. Calhoun taking to the press to debate the nature of power and liberty under the pseudonyms "Patrick Henry" and "Onslow". In the course of this exchange some of the most salient issues within American politics and liberty are debated, including the nature of political order, democracy, and the diffusion of political power.